"One of our problems is that we humans cannot live without acting; we have to act. Moreover, we have to act on the basis of what we know, and what we know is incomplete. What we have come to know so far is demonstrably incomplete, since we keep on learning more, and there seems little reason to think that our knowledge will become significantly more complete. The mystery surrounding our life probably is not significantly reducible. And so the question of how to act in ignorance is paramount."
-- Wendell Berry, Life is a Miracle